- inverse agonist
- инвертный агонист
English-Russian Biotechnology Glossary. A. F. Valikhov, V. V. Kolotvin, O. A. Legonkova, I. A. Rogov, Thomas Creamer. 2007.
inverse agonist
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Inverse agonist — In pharmacology, an inverse agonist is an agent which binds to the same receptor binding site as an agonist for that receptor and reverses constitutive activity of receptors. [cite journal |author=Kenakin T |title=Principles: receptor theory in… … Wikipedia
inverse agonist — (= reverse antagonist) Any ligand that binds to receptors and reduces the proportion in the active form. Has the opposite effects to an agonist and may actually reduce the background level of activity. Not the same as a partial agonist … Dictionary of molecular biology
Agonist (disambiguation) — Agonist may refer to: *An advocate of the political theory of agonism (or agonistic pluralism ). *Agonist, a substance that binds to a receptor to induce a biochemical response **Inverse agonist, a substance that induces the opposite effect of an … Wikipedia
Agonist — For other meanings of agonist or agonism , see agonist (disambiguation). For a primary fictional character in a work, see Protagonist and Antagonist. Agonists … Wikipedia
Agonist (Pharmakologie) — Dosis Wirkungskurven von Agonisten, die zu einer vollen (voller Agonist) oder partiellen Aktivierung eines Rezeptors führen (Partialagonist). Als Agonist (griechisch αγωνιστής, agonistís der Tätige, Handelnde, Führende) wird in der Pharmakologie… … Deutsch Wikipedia
Nicotinic agonist — A nicotinic agonist is a drug which enhances the action at the nicotinic acetylcholine receptor (nAChR). Examples include: nicotine (by definition the nicotinic acetylcholine receptor is named for its affinity for nicotine) acetylcholine, the… … Wikipedia
Dopamine agonist — Dopamine A dopamine agonist is a compound that activates dopamine receptors in the absence of dopamine. Dopamine agonists activate signaling pathways through the dopamine receptor and trimeric G proteins, ultimately leading to changes in gene… … Wikipedia
Muscarinic agonist — Muscarine A muscarinic receptor agonist is an agent that enhances the activity of the muscarinic acetylcholine receptor. The muscarinic receptor has different subtypes, labelled M1 M5, allowing for further differentiation. Contents 1 Clinical… … Wikipedia
Inverser Agonist — Dosis Wirkungskurve eines inversen Agonisten im Vergleich zu einem vollen Agonisten. Als inverse Agonisten werden in der Pharmakologie Substanzen bezeichnet, die an einen spontanaktiven Rezeptor binden und dessen Aktivität herabsetzen. Ein… … Deutsch Wikipedia
Receptor antagonist — This article is about the biochemistry term. For other uses, see Antagonist (disambiguation). Antagonists will block the binding of an agonist at a receptor molecule, inhibiting the signal produced by a receptor agonist coupling. A receptor… … Wikipedia
Cannabinoid receptor antagonist — The discovery of the endogenous cannabinoid system led to the development of CB1 receptor antagonists. The first cannabinoid receptor antagonist, rimonabant, was described in 1994. Rimonabant blocks the CB1 receptor selectively and it has been… … Wikipedia
